By David Taylor, Carol Paton
Case experiences in Psychopharmacology is an authoritative textual content written by way of pharmacists for pharmacists, medical professionals and nurses operating in psychiatry. The members, all revered specialists of their box, use case reports drawn from their very own broad services to demonstrate the selections made in treating sufferers being affected by quite a lot of psychiatric issues. those vignettes bring up vital questions referring to administration. The bankruptcy authors systematically evaluate the entire to be had proof, offering moderate administration judgements to lead the day by day treatment of the sufferers. the result's a realistic and entire ebook, offering thought of and well-supported recommendation at the use of psychotropics in the entire universal healing parts encountered in psychiatric and basic perform.
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Extra resources for Case Studies in Psychopharmacology: The Use of Drugs in Psychiatry
A 1181-4. review of its pharmacodynamic and pharmacokinetic properties and therapeutic Tollefson GD, Beasley CM, Tran PV et al efficacy in the management of (1997) Olanzapine versus haloperidol in the schizophrenia, CNS Drugs 9: 153-75. treatment of schizophrenia and schizoaffective Rifkin A, Doddi S, Karajgi B et al (1991) Dosage of haloperidol for schizophrenia, Arch Gen Psychiatry 48: 166-70. and schizophreniform disorders: results of an international collaborative trial, Am J Psychiatry 154: 457-65.
If dose adjustment or reduction is not possible, hypertension can be treated with ~-blockers, seizures with valproate and UI with anticholinergics or desmopressin. References Antelo RE, Stanilla JK, Martin-Lionch N (1994) Myoclonic seizures and 'leg folding' phenomena with clozapine therapy: report of two cases, Bioi Psychiatry 36: 759-62. Managing adverse effects of clozapine Aponowitz JS, Safferman AZ, Lieberman JA 37 (1994) Clozapine dose in the United States (1995) Management of clozapine-induced and Europe: implications for therapeutic and enuresis, Am J Psychiatry 152: 472.
1996; Sajatovic and Meltzer, 1996). The true incidence is unclear. However, it appears that the risk of a seizure with clozapine increases with increased doses (plasma concentrations) (Pacia and Devinsky, 1994) and is greatest with doses of 600 mg daily or greater. , 1994) comparing 35 clozapine doses used in European trials with those used in American trials, the authors found that in the higher dosed American trials, seizures were more prevalent. Seizures may also occur during dosage titration when clozapine is initiated, particularly if the dose is increased rapidly.
Case Studies in Psychopharmacology: The Use of Drugs in Psychiatry by David Taylor, Carol Paton